Feng Huang , Xiaoyu Du , Shaokui Zou , Lina Wang , Yulin Han

Zhoukou Academy of Agricultural Sciences, Zhoukou, 466001, Henan, China
Author    Correspondence author
Plant Gene and Trait, 2024, Vol. 15, No. 4   
Received: 22 Jun., 2024    Accepted: 23 Jul., 2024    Published: 31 Jul., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The MlWE74 gene, a novel powdery mildew resistance gene, has garnered widespread attention for its potential to enhance disease resistance in wheat. This study provides a comprehensive summary of the positional cloning, functional analysis, and breeding application of the wheat powdery mildew resistance gene MlWE74. A systematic analysis of the cloning strategy, functional mechanisms, and its application in molecular breeding was conducted, evaluating its contributions to disease resistance improvement and its practical value in modern wheat breeding. The findings reveal that the MlWE74 gene holds significant potential for use in wheat disease resistance breeding. Its functional analysis and breeding applications will further advance the development of resistant wheat varieties. Future research should focus on in-depth studies of the MlWE74 gene, combining gene editing and multi-gene resistance strategies to enhance its breeding efficiency. The successful cloning and functional analysis of the MlWE74 gene offer new perspectives and tools for the development of powdery mildew-resistant wheat varieties. With the advancement of genome selection, marker-assisted breeding, and gene editing technologies, the application of MlWE74 is expected to greatly improve disease resistance in wheat varieties, contributing to global food security.

Wheat; Powdery mildew; MlWE74 gene; Positional cloning; Molecular breeding